Sleep apnea is a common, chronic sleep disorder characterized by repeated pauses in breathing during sleep. These interruptions reduce oxygen levels, fragment sleep, and place significant strain on the cardiovascular, metabolic, and neurological systems.

An estimated 83.7 million Americans suffer from sleep apnea, with an estimated 80% remaining undiagnosed.

Untreated OSA is strongly associated with increased risks of hypertension, cardiovascular disease, stroke, Type 2 diabetes, cognitive impairment, and increased all-cause mortality.

Disease- people with moderate to severe sleep apnea are:

• 4X more likely to die from any cause over long-term follow-up than those without OSA.

• 4X more likely to experience a stroke compared to people without significant OSA.

• 5X more likelyto experience cancer-specific mortality in some long-term cohort data.

Mental health- people with sleep apnea:

·      Report marked deficits in physical functioning, social engagement, emotional well-being, and energy levels compared with people without OSA.

·      2X more likely to develop Alzheimer’s disease.

Medicare currently reimburses:

·      CPAP therapy: adherence is often low- only ~45 % of patients remaining adherent at 90 days and ~44.7 % at 12 months after starting therapy

·      Hypoglossal nerve stimulation options (e.g., “Thrive”/Inspire/Apnex) show wide variability in success for sleep apnea ranging from 55-77% effectiveness after 12 months

·      Oral appliance therapy appliances have historically been difficult for many patients to access due to limited provider availability and administrative barriers, yet they typically have high compliance rates with median nightly use around 6–6.4 hours and ~82% classified as compliant after several months of therapy

Sleep Apnea contributes significantly to motor vehicle collisions, healthcare costs, work limitations, and reduced quality of life.

The annual economic burden of undiagnosed sleep apnea in the U.S. has been estimated at ≈ $149.6 billion, including:

·       $86.9 billion in lost productivity

·       $26.2 billion from motor vehicle accidents

·       $6.5 billion from workplace accidents, 

·       $30 billion from increased healthcare utilization and medication costs associated with comorbid conditions (e.g., hypertension, diabetes).